Are ethics rules too strict in retrospective clinical studies?

Ethics in Clinical Research

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Too early for global ethics?

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Are all pulmonary embolism clinical decision rules

Clinical question Are four common clinical decision rules, in combination with normal D-dimer results, comparable in their ability to clinically exclude the diagnosis of pulmonary embolism? Article chosen Douma RA, Mos ICM, Erkens PMG, et al. Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort study. Ann Intern Med 2011;154:709...

When Deer Are Too Dear and Elk Are Too Elegant

Are There Clinical Cardiac Complications From Too Much Exercise?

Introduction The dose-response association between physical activity and cardiovascular outcomes is well described (10). As little as 15 minId of moderate-intensity exercise significantly lowers the risk for cardiovascular morbidity and mortality. Greater volumes yield greater cardiovascular benefit. However, the impact of extreme volumes of exercise on cardiovascular health is under debate (9)...